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Stomatologija 2020; 22 (1): 28-32 273 KB

Clear cell odontogenic carcinoma: a rare pathology with an innovative resolution

Natalia Lucía Gómez^*, Luis Boccalatte^*, Alejandro Yanzón^*, María Gabriela Nassif^*, Juan José Larrañaga^*, Marcelo Fernando Figari^*

Summary

Clear cell odontogenic carcinoma (CCOC) is an uncommon condition that has been considered malignant since 2005. The clinical presentation usually involves an asymptomatic swelling, which typically affects the anterior mandible in middle-aged women; it has neither clinical nor radiological defining features. Immunohistochemical analysis usually aids diagnosis, as clear cells are also associated with other clear cell carcinomas and benign tumors. Radical surgery is the gold standard of treatment and usually needs microsurgical reconstruction with bone transference for restoration of facial anatomy and adequate function.

We present the case of a young woman with CCOC whose tumor removal and reconstructive surgery were planned virtually and assisted by intraoperative navigation. The novelty of the reconstructive procedure was the replacement of the fibula cutting guides for intraoperative navigation of the osteotomies. We present a brief review of CCOC and the benefits of using computer-assisted surgery (CAS) in high-complexity cases like this one.

Key words: clear cell odontogenic tumors, virtual planning, intraoperative navigation.

Received: 03 03 2018

Accepted for publishing: 21 03 2020

^*Head and Neck Section, General Surgery Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

Address correspondence to Natalia Lucía Gómez, Head and Neck Section, General Surgery Service, Hospital Italiano de Buenos Aires, Paraguay 4092 2 A, Buenos Aires, Argentina, C.P.: 1425

E-mail address: lucia.gomez@hospitalitaliano.org.ar



	Baltic Dental and Maxillofacial Journal

March, 2020, Vol. 22, No. 1 CONTENTS SCIENTIFIC ARTICLES Tendencies of FGFR2 rs2981582 polymorphism in patients with oral cancer Vykintas Liutkevicius, Toma Tamauskaite, Alvita Vilkeviciute, Rasa Liutkeviciene, Rasa Smalinskaite, Agne Giedraitiene, Alina Smalinskiene, Virgilijus Uloza 3-8 REVIEWS Basal Cell Carcinoma. Analysis of 395 cases localized in the neck, ear and nose region Egils Kornevs, Ingus Arnolds Apse, Toms Janis Safronovs, Aija Krastina, Arturs Paparde, Gunars Lauskis, Girts Salms 9-16 Sodium hypochlorite accidents in dentistry. A systematic review of published case reports Shishir Ram Shetty, Sura Ali Ahmed Fuoad Al-Bayati, Ashwin Narayanan, Mohammed Said Hamed, Hossam Abdelatty Eid Abdemagyd, Praveen Shetty 17-22 Autologous platelet concentrates in treatment of medication related osteonecrosis of the jaw Henrikas Rusilas, Aušra Balčiūnaitė, Juozas Žilinskas 23-27 CASE REPORT Clear cell odontogenic carcinoma: a rare pathology with an innovative resolution Natalia Lucía Gómez, Luis Boccalatte, Alejandro Yanzón, María Gabriela Nassif, Juan José Larrañaga, Marcelo Fernando Figari 28-32 © 2020 Stomatologija		Stomatologija 2020; 22 (1): 28-32 273 KB Clear cell odontogenic carcinoma: a rare pathology with an innovative resolution Natalia Lucía Gómez^, Luis Boccalatte^, Alejandro Yanzón^, María Gabriela Nassif^, Juan José Larrañaga^, Marcelo Fernando Figari^ Summary Clear cell odontogenic carcinoma (CCOC) is an uncommon condition that has been considered malignant since 2005. The clinical presentation usually involves an asymptomatic swelling, which typically affects the anterior mandible in middle-aged women; it has neither clinical nor radiological defining features. Immunohistochemical analysis usually aids diagnosis, as clear cells are also associated with other clear cell carcinomas and benign tumors. Radical surgery is the gold standard of treatment and usually needs microsurgical reconstruction with bone transference for restoration of facial anatomy and adequate function. We present the case of a young woman with CCOC whose tumor removal and reconstructive surgery were planned virtually and assisted by intraoperative navigation. The novelty of the reconstructive procedure was the replacement of the fibula cutting guides for intraoperative navigation of the osteotomies. We present a brief review of CCOC and the benefits of using computer-assisted surgery (CAS) in high-complexity cases like this one. Key words: clear cell odontogenic tumors, virtual planning, intraoperative navigation. Received: 03 03 2018 Accepted for publishing: 21 03 2020 ^*Head and Neck Section, General Surgery Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina Address correspondence to Natalia Lucía Gómez, Head and Neck Section, General Surgery Service, Hospital Italiano de Buenos Aires, Paraguay 4092 2 A, Buenos Aires, Argentina, C.P.: 1425 E-mail address: lucia.gomez@hospitalitaliano.org.ar