Baltic Dental and Maxillofacial Journal
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March, 2020, Vol. 22, No. 1

CONTENTS

SCIENTIFIC ARTICLES

Tendencies of FGFR2 rs2981582 polymorphism in patients with oral cancer
Vykintas Liutkevicius, Toma Tamauskaite, Alvita Vilkeviciute, Rasa Liutkeviciene, Rasa Smalinskaite, Agne Giedraitiene, Alina Smalinskiene, Virgilijus Uloza
3-8

REVIEWS

Basal Cell Carcinoma. Analysis of 395 cases localized in the neck, ear and nose region
Egils Kornevs, Ingus Arnolds Apse, Toms Janis Safronovs, Aija Krastina, Arturs Paparde, Gunars Lauskis, Girts Salms

9-16

Sodium hypochlorite accidents in dentistry. A systematic review of published case reports
Shishir Ram Shetty, Sura Ali Ahmed Fuoad Al-Bayati, Ashwin Narayanan, Mohammed Said Hamed, Hossam Abdelatty Eid Abdemagyd, Praveen Shetty

17-22

Autologous platelet concentrates in treatment of medication related osteonecrosis of the jaw
Henrikas Rusilas, Aušra Balčiūnaitė, Juozas Žilinskas

23-27

CASE REPORT

Clear cell odontogenic carcinoma: a rare pathology with an innovative resolution
Natalia Lucía Gómez, Luis Boccalatte, Alejandro Yanzón, María Gabriela Nassif, Juan José Larrañaga, Marcelo Fernando Figari
28-32


© 2020 Stomatologija

Stomatologija 2020; 22 (1): 9-16 378 KB

Basal Cell Carcinoma. Analysis of 395 cases localized in the neck, ear and nose region

Egils Kornevs1,2, Ingus Arnolds Apse3,4, Toms Janis Safronovs3, Aija Krastina6, Arturs Paparde5, Gunars Lauskis1,2, Girts Salms1,7

Summary

Background and objectives. To test if there are different outcomes in basal cell carcinoma for lesion size, histopathology, localization, and recurrence rates.

Materials and methods. A total of 395 patients with BCC localized in the neck, nose and ear regions who were surgically treated in Latvian Oncology Centre between 2006-2011 were analyzed retrospectively. The data were analyzed using modified classification based on Clarks et al. (2014) and McKenzie et al. (2016).

Results. Three hundred and ninety-five cases of BCC that were surgically treated in head and neck region were reviewed. Results were tabulated in four categories: anatomical region, histopathology, lesion size, and recurrence rates. Classification by anatomical region: 228 cases in the nose region, 82 cases in the neck region, 82 cases in the ear region. Classification by histopathology: 259 cases presented as low risk BCC [nodular, pigmented, adenoid, keratotic and cystic], 21 cases presented as superficial, 94 cases presented as mixed, and 21 cases presented as high-risk BCC (metatypical, morphea form). Mann-Whitney U test was used to compare recurrent BCC cases to non-recurrent cases. Significantly higher recurrence rates were observed if BCC at the time of the excision was ≥ 10mm (p<0.001). Significance was also noted in cases where histopathology was mixed BCC and in cases where mixed BCC was localized to the nose region (p<0.001).

Conclusion. More attention should be brought to assessing classification and clinical treatment synergy. Higher recurrence rates are observed when lesions occur in high risk anatomical region (H zone), when lesion size reaches or exceeds 20 mm in diameter, and when lesion is subtyped as mixed BCC. It is crucial to evaluate risk factors such as BCC subtype and localization, as these are associated with a higher rate of recurrence when present in a single lesion. These risk factors, together with pre-treatment lesion evaluation will enable formulation of better treatment plan and prognostic aspects in each case.

Key words: basal cell carcinoma, recurrence, head and neck oncology, non-melanoma skin cancer.

Received: 17 12 2019

Accepted for publishing: 21 03 2020


1Department of Oral and Maxillofacial Surgery, Riga Stradiņš University, Riga, Latvia

2Department of Head and Neck surgery, Oncology Centre of Latvia, Riga East Clinical University Hospital, Riga, Latvia

3Faculty of Medicine, Riga Stradiņš University, Riga, Latvia

4Faculty of Dentistry, Riga Stradiņš University, Riga, Latvia

5Department of Human physiology and biochemistry, Riga Stradiņš University, Riga, Latvia

6Department of Anesthesiology and Intensive Therapy, Oncology Centre of Latvia, Riga East Clinical University Hospital, Riga, Latvia

7Department of Maxillofacial Surgery, Oncology Centre of Latvia, Riga East Clinical University Hospital, Riga, Latvia

Address correspondence to Ingus Arnolds Apse, Department of Oral and Maxillofacial Surgery, Riga Stradiņš University, Riga, Latvia.

E-mail: apseingus@gmail.com