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Stomatologija 2014; 16 (4): 137-143 603 KB

Mandibular morphology in monozygotic twins: a cephalometric study

Mantas Šidlauskas, Loreta Šalomskienė, Irena Andriuškevičiūtė, Monika Šidlauskienė, Žygimantas Labanauskas, Antanas Šidlauskas

Summary

Background. The understanding of relative effects of genetics and environmental factors on mandible growth would increase effectiveness of orthodontic therapy and treatment planning. The purpose of this study was to clarify whether the skeletal morphology of mandible is phenotypically alike in two individuals in a pair of young adult monozygotic (MZ) twins.

Methods. The 90 twin pairs were classified as MZ by 15 specific DNA markers and Amel fragment. Cephalometric analysis of mandible morphology using 27 parameters was done and Pearson’s intra-pair correlation coefficient for each variable was calculated.

Results. The highest correlations of cephalometric variables between two individuals in the same MZ twins pair was in the total mandibular and corpus length (r=0.94). The lowest correlations was established for depth of antigonial notch (r=0.65) and articular angle (r=0.68) in female pairs. Statistically significant differences (p≤0.05) of intra-pair correlation coefficients between genders was found only for total mandibular length (distances Co-Gn and Ar-Gn).

Conclusions. Mandibular length has highest intra-pair correlation coefficient among similar linear cephalometric variables in MZ twins. The females demonstrated greater variability of mandible skeletal cephalometric measurements within the MZ twin pair than the men.

Key words: mandible, monozygotic twins, cephalometrics.

Received: 18 01 2014

Accepted for publishing: 20 12 2014

¹Clinic of Orthodontics, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

²Institute of Biology Systems and Genetics, Veterinary Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

³Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

Mantas Šidlauskas¹ – D.D.S

Loreta Šalomskienė² – PhD

Irena Andriuškevičiūtė² – PhD

Žygimantas Labanauskas³ – – student

Monika Šidlauskienė¹ – D.D.S.

Antanas Šidlauskas¹ – D.D.S., PhD, MOrthRCSEd, prof.

Address correspondence to Mantas Šidlauskas, Clinic of Orthodontics, Medical Academy, Lithuanian University of Health Sciences, J.Lukšos-Daumanto str. 6, LT -50106 Kaunas, Lithuania.

E-mail address: m.sidlauskas@gmail.com



	Baltic Dental and Maxillofacial Journal

December, 2014, Vol. 16, No. 4 CONTENTS REVIEWS Hemophilia and oral health Ruta Zaliuniene, Vytaute Peciuliene, Vilma Brukiene, Jolanta Aleksejuniene 127-131 SCIENTIFIC ARTICLES IRF6 AP-2a binding site promoter polymorphism is associated with oral clefts in Latvia Kristīne Krasone, Baiba Lāce, Ilze Akota, Rūta Care, Kathleen Deeley, Erika C. Küchler, Alexandre R. Vieira 132-136 Mandibular morphology in monozygotic twins: a cephalometric study Mantas Šidlauskas, Loreta Šalomskienė, Irena Andriuškevičiūtė, Monika Šidlauskienė, Žygimantas Labanauskas, Antanas Šidlauskas 137-143 Quality management and job related factors predicting satisfaction of dental clinic staff in Estonia Eda Merisalu, Georg Männik, Kaja Põlluste 144-152 REVIEWS Biologically active substances in bone morphogenesis. Literature review Stasys Bojarskas, Regimantas Simuntis 153-160 © 2014 Stomatologija		Stomatologija 2014; 16 (4): 137-143 603 KB Mandibular morphology in monozygotic twins: a cephalometric study Mantas Šidlauskas, Loreta Šalomskienė, Irena Andriuškevičiūtė, Monika Šidlauskienė, Žygimantas Labanauskas, Antanas Šidlauskas Summary Background. The understanding of relative effects of genetics and environmental factors on mandible growth would increase effectiveness of orthodontic therapy and treatment planning. The purpose of this study was to clarify whether the skeletal morphology of mandible is phenotypically alike in two individuals in a pair of young adult monozygotic (MZ) twins. Methods. The 90 twin pairs were classified as MZ by 15 specific DNA markers and Amel fragment. Cephalometric analysis of mandible morphology using 27 parameters was done and Pearson’s intra-pair correlation coefficient for each variable was calculated. Results. The highest correlations of cephalometric variables between two individuals in the same MZ twins pair was in the total mandibular and corpus length (r=0.94). The lowest correlations was established for depth of antigonial notch (r=0.65) and articular angle (r=0.68) in female pairs. Statistically significant differences (p≤0.05) of intra-pair correlation coefficients between genders was found only for total mandibular length (distances Co-Gn and Ar-Gn). Conclusions. Mandibular length has highest intra-pair correlation coefficient among similar linear cephalometric variables in MZ twins. The females demonstrated greater variability of mandible skeletal cephalometric measurements within the MZ twin pair than the men. Key words: mandible, monozygotic twins, cephalometrics. Received: 18 01 2014 Accepted for publishing: 20 12 2014 ¹Clinic of Orthodontics, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania ²Institute of Biology Systems and Genetics, Veterinary Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania ³Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania Mantas Šidlauskas¹ – D.D.S Loreta Šalomskienė² – PhD Irena Andriuškevičiūtė² – PhD Žygimantas Labanauskas³ – – student Monika Šidlauskienė¹ – D.D.S. Antanas Šidlauskas¹ – D.D.S., PhD, MOrthRCSEd, prof. Address correspondence to Mantas Šidlauskas, Clinic of Orthodontics, Medical Academy, Lithuanian University of Health Sciences, J.Lukšos-Daumanto str. 6, LT -50106 Kaunas, Lithuania. E-mail address: m.sidlauskas@gmail.com