www.sbdmj.com - Stomatologija - Baltic Dental and Maxillofacial Journal

Stomatologija 2025; 27 (1): 20-4 134 KB

Post-traumatic oral necrosis in a patient with refractory epilepsy: A case report

Lukas Mendes de Abreu¹, Tamara Fernandes de Castro¹, Giseli Mitsuy Kayahara^{1, 2}, Vitor Bonetti Valente^{1, 2}, Gisele Zoccal Mingoti³, Glauco Issamu Miyahara^{1, 2}, Éder Ricardo Biasoli^{1, 2}, Daniel Galera Bernabé^{1, 2}

Summary

Epilepsy patients can show a wide range of oral and maxillofacial injuries after seizures. However, the occurrence of oral soft tissue necrosis (OSTN) has been rarely reported. In the current report, a 55-year-old man with refractory epilepsy was referred for evaluation of an extensive injury in the oral mucosa after a severe seizure. Intraoral examination revealed a painless grayish-white necrotic area in the posterior region of the buccal mucosa on the left side measuring about 2×3 cm. Clinical findings led to the diagnosis of post-traumatic OSTN and the patient underwent surgical debridement on an outpatient basis. Two-month follow-up showed complete healing associated with the formation of fibrous tissue. A review of the literature demonstrated that post-traumatic OSTN was not reported among oral and/or maxillofacial injuries found in epilepsy patients. However, the current report reinforces that soft tissue necrosis may occur in the oral cavity of these patients after seizures. Post-traumatic OSTN should be considered an oral injury found in patients with refractory epilepsy.

Key words: epilepsy, maxillofacial injuries, oral injuries, necrosis, oral soft tissue necrosis.

Received: 08 09 2022

Accepted for publishing: 24 03 2025

¹Oral Oncology Center, São Paulo State University (Unesp), School of Dentistry, São Paulo, Brazil

²Department of Diagnosis and Surgery, São Paulo State University (Unesp), School of Dentistry, São Paulo, Brazil 3Laboratory of Reproductive Physiology, Department of Animal Health, School of Veterinary Medicine, São Paulo State University (Unesp), São Paulo, Brazil.

Address correspondence to Daniel Galera Bernabé, Oral Oncology Center, São Paulo State University (Unesp), School of Dentistry, 1193 José Bonifácio St, SP 15050-015, Araçatuba, São Paulo, Brazil.

E-mail address: daniel.bernabe@unesp.br



	Baltic Dental and Maxillofacial Journal

2025, Vol. 27, No. 1 CONTENTS SCIENTIFIC ARTICLES Narrow diameter titanium dental implants fracture resistance after implantoplasty Osvaldas Mickevičius, Artūras Pauliukevičius 3-8 Dental anomalies in subjects with non-syndromic cleft lip and palate Soundarya Sakthivel, Vidya Ajila, Subhas Babu, Vikram Shetty, Shruthi Hegde, Anwesha Biswas 9-16 CASE REPORTS An unusual relationship of spinal accessory nerve and internal jugular vein – An alert for the oral and maxillofacial surgeon Amit S. Date, Mukul Padhye, Yogesh Kini 17-19 Post-traumatic oral necrosis in a patient with refractory epilepsy: A case report Lukas Mendes de Abreu, Tamara Fernandes de Castro, Giseli Mitsuy Kayahara,Vitor Bonetti Valente, Gisele Zoccal Mingoti, Glauco Issamu Miyahara, Éder Ricardo Biasoli, Daniel Galera Bernabé 20-24 © 2025 Stomatologija		Stomatologija 2025; 27 (1): 20-4 134 KB Post-traumatic oral necrosis in a patient with refractory epilepsy: A case report Lukas Mendes de Abreu¹, Tamara Fernandes de Castro¹, Giseli Mitsuy Kayahara^{1, 2}, Vitor Bonetti Valente^{1, 2}, Gisele Zoccal Mingoti³, Glauco Issamu Miyahara^{1, 2}, Éder Ricardo Biasoli^{1, 2}, Daniel Galera Bernabé^{1, 2} Summary Epilepsy patients can show a wide range of oral and maxillofacial injuries after seizures. However, the occurrence of oral soft tissue necrosis (OSTN) has been rarely reported. In the current report, a 55-year-old man with refractory epilepsy was referred for evaluation of an extensive injury in the oral mucosa after a severe seizure. Intraoral examination revealed a painless grayish-white necrotic area in the posterior region of the buccal mucosa on the left side measuring about 2×3 cm. Clinical findings led to the diagnosis of post-traumatic OSTN and the patient underwent surgical debridement on an outpatient basis. Two-month follow-up showed complete healing associated with the formation of fibrous tissue. A review of the literature demonstrated that post-traumatic OSTN was not reported among oral and/or maxillofacial injuries found in epilepsy patients. However, the current report reinforces that soft tissue necrosis may occur in the oral cavity of these patients after seizures. Post-traumatic OSTN should be considered an oral injury found in patients with refractory epilepsy. Key words: epilepsy, maxillofacial injuries, oral injuries, necrosis, oral soft tissue necrosis. Received: 08 09 2022 Accepted for publishing: 24 03 2025 ¹Oral Oncology Center, São Paulo State University (Unesp), School of Dentistry, São Paulo, Brazil ²Department of Diagnosis and Surgery, São Paulo State University (Unesp), School of Dentistry, São Paulo, Brazil 3Laboratory of Reproductive Physiology, Department of Animal Health, School of Veterinary Medicine, São Paulo State University (Unesp), São Paulo, Brazil. Address correspondence to Daniel Galera Bernabé, Oral Oncology Center, São Paulo State University (Unesp), School of Dentistry, 1193 José Bonifácio St, SP 15050-015, Araçatuba, São Paulo, Brazil. E-mail address: daniel.bernabe@unesp.br