www.sbdmj.com - Stomatologija - Baltic Dental and Maxillofacial Journal

Stomatologija 2019; 21 (2): 35-41 108 KB

The topical effect of chlorhexidine and povidone-iodine in the repair of oral wounds. A review

Dieni da Silveira Teixeira¹, Maria Antonia Zancanaro de Figueiredo¹, Karen Cherubini¹, Sílvia Dias de Oliveira², Fernanda Gonçalves Salum¹

Summary

Purpose. The aim of this paper was to review the current literature with regard to the use of chlorhexidine and povidone-iodine in the treatment of oral wounds.

Background. Oral mucosa is continuously subjected to physical or chemical injuries, where it becomes a common site for the occurrence of ulcerated lesions. These lesions are susceptible to infections that may delay healing.

Materials and methods. A search of the medical and dental literature was conducted in Medline/Pubmed and Scielo using a combination of the terms oral ulcer, oral wound, wound healing, povidone-iodine and chlorhexidine, to review their mechanism of action and their use in the healing of oral wounds.

Results and conclusion. The use of chlorhexidine and povidone-iodine is effective in the control of local infection in a concentration-dependent manner, exerting a positive influence on the tissue repair process. Oral antiseptics appear be a good alternative in the management of these lesions, since there is a low risk of systemic toxicity and allergies, and less clinical evidence of bacterial resistance.

Key words: Chlorhexidine, Povidone-Iodine, Wound Healing, Oral Wound.

Received: 03 12 2017

Accepted for publishing: 21 06 2019

¹Oral Medicine Division, São Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil

²School of Health and Life Sciences, Laboratory of Immunology and Microbiology, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil

Address correspondence to Dieni da Silveira Teixeira, Serviço de Estomatologia, Hospital São Lucas, PUCRS, Av. Ipiranga, 6690 Room 231, CEP: 90610-000, Porto Alegre, RS, Brazil.

E-mail address: dieni.teixeira@acad.pucrs.br



	Baltic Dental and Maxillofacial Journal

June, 2019, Vol. 21, No. 2 CONTENTS REVIEWS The topical effect of chlorhexidine and povidone-iodine in the repair of oral wounds. A review Dieni da Silveira Teixeira, Maria Antonia Zancanaro de Figueiredo, Karen Cherubini, Sílvia Dias de Oliveira, Fernanda Gonçalves Salum 35-41 SCIENTIFIC ARTICLES Dental anxiety and self-perceived stress in Lithuanian University of Health sciences hospital patients. A cross-sectional study Ignas Barauskas, Kamilė Barauskienė, Gintaras Janužis 42-46 Effects of fruit drinks on surface roughness of two esthetic restorative materials Faika Y. Abdelmegid, Fouad S. Salama, Mohammad M. Al-Jameel, Talal T. Al-Rasheed, Mohamed A. El-Sharawy 47-52 CASE REPORT Diagnostic sequence for early diagnosis of neurofibromatosis type 1 using NIH criteria Tiago Novaes Pinheiro, Fernanda Vicioni-Marques, Flavio Tendolo Fayad, Pedro Henrique Ribeiro Arantes, Juliana Arid, Mariana de Oliveira Daltoé, Fabio Marinho Furtado, Fabrício Kitazono de Carvalho 53-56 Mandibular buccal bifurcation cyst: Case report and literature review Larissa Porto Lima, Henrique Côrtes Meira, Tânia Mara Pimenta Amaral, Patrícia Carlos Caldeira, Evandro Neves Abdo, Cláudia Borges Brasileiro 57-61 Prosthetic solution for fixed full-arch maxillary prosthesis with implant divergent parallelism greater than 45°. A case report Gustavo Frainer Barbosa, Daniele Pereira Dotto 62-64 © 2019 Stomatologija		Stomatologija 2019; 21 (2): 35-41 108 KB The topical effect of chlorhexidine and povidone-iodine in the repair of oral wounds. A review Dieni da Silveira Teixeira¹, Maria Antonia Zancanaro de Figueiredo¹, Karen Cherubini¹, Sílvia Dias de Oliveira², Fernanda Gonçalves Salum¹ Summary Purpose. The aim of this paper was to review the current literature with regard to the use of chlorhexidine and povidone-iodine in the treatment of oral wounds. Background. Oral mucosa is continuously subjected to physical or chemical injuries, where it becomes a common site for the occurrence of ulcerated lesions. These lesions are susceptible to infections that may delay healing. Materials and methods. A search of the medical and dental literature was conducted in Medline/Pubmed and Scielo using a combination of the terms oral ulcer, oral wound, wound healing, povidone-iodine and chlorhexidine, to review their mechanism of action and their use in the healing of oral wounds. Results and conclusion. The use of chlorhexidine and povidone-iodine is effective in the control of local infection in a concentration-dependent manner, exerting a positive influence on the tissue repair process. Oral antiseptics appear be a good alternative in the management of these lesions, since there is a low risk of systemic toxicity and allergies, and less clinical evidence of bacterial resistance. Key words: Chlorhexidine, Povidone-Iodine, Wound Healing, Oral Wound. Received: 03 12 2017 Accepted for publishing: 21 06 2019 ¹Oral Medicine Division, São Lucas Hospital, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil ²School of Health and Life Sciences, Laboratory of Immunology and Microbiology, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Porto Alegre, Brazil Address correspondence to Dieni da Silveira Teixeira, Serviço de Estomatologia, Hospital São Lucas, PUCRS, Av. Ipiranga, 6690 Room 231, CEP: 90610-000, Porto Alegre, RS, Brazil. E-mail address: dieni.teixeira@acad.pucrs.br