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Stomatologija 2018; 20 (4): 111-8 249 KB

Efficacy of autologous platelet rich fibrin in bone augmentation and bone regeneration at extraction socket

Bernard Blinstein¹, Stasys Bojarskas²

Summary

Objective. The purpose of the present study is to provide the efficacy of autologous platelet rich fibrin in bone augmentation and bone regeneration procedures in regard of soft and hard tissue healing in oral surgery treatment.

Material and methods. An electronic search on PubMed database was performed regarding the placement of autologous platelet rich fibrin at tooth extraction sockets, bone and soft tissue augmentation procedures associated with implant placement and infrabony defects. The search was constrained to English language articles published during last five years and includes only clinical trials.

Results. In total, 25 articles were included in this literature review. The studies were divided into five main groups, depending on the application: 1) utilization of autologous platelet rich fibrin at 3rd molar extraction sockets preservation, 2) any extraction socket preservation, 3) bone augmentation/sinus lift procedures with implant placement, 4) augmentation of peri-implant tissues, and 5) treatment of infrabony defects.

Conclusions. The application of autologous platelet rich fibrin (PRF) show benefits in promoting soft tissue healing and bone regeneration in different surgical procedures. Furthermore, it is an autologous biomaterial which has low cost and does not need administration of any additives. Nevertheless, further studies with a bigger sample size and longer follow up duration are necessary to facilitate more substantial evidence of the efficacy of PRF in promotion of soft and hard tissue healing.

Key words: platelet rich fibrin, bone regeneration, soft tissue healing, bone augmentation.

Received: 17 04 2017

Accepted for publishing: 25 12 2018

¹Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

²Department of Oral and Maxillofacial surgery Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

Address correspondence to Stasys Bojarskas, Department of Oral and Maxillofacial Surgery, Medical Academy, Lithuanian University of Health Sciences, Eivenių str. 2, 50009, Kaunas, Lithuania.

E-mail address: litmaxfac@yahoo.com



	Baltic Dental and Maxillofacial Journal

December, 2018, Vol. 20, No. 4 CONTENTS REVIEWS Efficacy of autologous platelet rich fibrin in bone augmentation and bone regeneration at extraction socket Bernard Blinstein, Stasys Bojarskas 111-118 SCIENTIFIC ARTICLES Influence of light-curing unit on the network structure and mechanical properties of model resin cements containing diphenyliodonium compared with a commercial reference Ailla Carla Lancellotti, Luciano Souza Gonçalves, Adriano Fonseca Lima, Alan Rodrigo Palialol, Simonides Consani 119-124 Clinical substantiation of the sparing and less invasive implant prosthetics of the edentulous lower jaw method Vladimir Trezubov, Yuri Parshin, Roman Rozov, Alexander Simonenko 125-129 Results of complex rehabilitation patients with temporomandibular joint disease and parafunction of masticatory muscles Roman Fadeyev, Vasiliy Parshin 130-138 The prevalence of facial and dentolabial parameters among students of the Faculty of Dentistry of Lithuanian University of Health Sciences Eglė Mickevičiūtė, Dovilė Bitinienė, Gediminas Žekonis, Jurgina Sakalauskienė, Juozas Žilinskas 139-144 © 2018 Stomatologija		Stomatologija 2018; 20 (4): 111-8 249 KB Efficacy of autologous platelet rich fibrin in bone augmentation and bone regeneration at extraction socket Bernard Blinstein¹, Stasys Bojarskas² Summary Objective. The purpose of the present study is to provide the efficacy of autologous platelet rich fibrin in bone augmentation and bone regeneration procedures in regard of soft and hard tissue healing in oral surgery treatment. Material and methods. An electronic search on PubMed database was performed regarding the placement of autologous platelet rich fibrin at tooth extraction sockets, bone and soft tissue augmentation procedures associated with implant placement and infrabony defects. The search was constrained to English language articles published during last five years and includes only clinical trials. Results. In total, 25 articles were included in this literature review. The studies were divided into five main groups, depending on the application: 1) utilization of autologous platelet rich fibrin at 3rd molar extraction sockets preservation, 2) any extraction socket preservation, 3) bone augmentation/sinus lift procedures with implant placement, 4) augmentation of peri-implant tissues, and 5) treatment of infrabony defects. Conclusions. The application of autologous platelet rich fibrin (PRF) show benefits in promoting soft tissue healing and bone regeneration in different surgical procedures. Furthermore, it is an autologous biomaterial which has low cost and does not need administration of any additives. Nevertheless, further studies with a bigger sample size and longer follow up duration are necessary to facilitate more substantial evidence of the efficacy of PRF in promotion of soft and hard tissue healing. Key words: platelet rich fibrin, bone regeneration, soft tissue healing, bone augmentation. Received: 17 04 2017 Accepted for publishing: 25 12 2018 ¹Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania ²Department of Oral and Maxillofacial surgery Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania Address correspondence to Stasys Bojarskas, Department of Oral and Maxillofacial Surgery, Medical Academy, Lithuanian University of Health Sciences, Eivenių str. 2, 50009, Kaunas, Lithuania. E-mail address: litmaxfac@yahoo.com