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Stomatologija 2015; 17 (3): 102-104 76 KB

Trichoadenoma of the upper lip

Gian Paolo Bombeccari, Gianpaolo Guzzi, Umberto Mariani, Andrea Gianatti, Diego Ruffoni, Franco Santoro, Francesco Spadari

Summary

Background. Trichoadenoma of Nikolowski, who describe the first cases in 1958, is a rare and benign tumor of the hair follicle. It is well-differentiated and slowly-growing. The clinical appearance of Trichoadenoma (TA) can be similar to basal cell carcinoma or epidermal cyst.

Results. We describe a 44-year-old male who was referred for nodular lesion on the upper lip and a TA was diagnosed. Oral examination showed exophytic yellow mass located between mucous membrane of the upper lip and vestibular gingiva, 1.2 per 0.8 cm. Anamnestic data was non-contributory. An excisional biopsy of the lesion was performed. Microscopically, the lesion consisted of multiple keratinous cysts lined with stratified squamous epithelium and intermingled with solid islands of basaloid cells lying within sclerotic stroma. The pathological diagnosis was TA. The surgical wound healed uneventfully.

Conclusion. Because the lesion is unique, it is uncertain how aggressive or indolent the tumor might be. Therefore, the microscopical analysis is mandatory. At the best of our knowledge, this is the second case of trichoadenoma of the lip.

Key words: lip lesion, oral nodule, lip tumor, oral tumor, oral follicular hamartoma.

Received: 28 07 2013

Accepted for publishing: 28 09 2015

¹Department of Biomedical, Surgical and Dental Sciences, Ospedale Maggiore Policlinico Fondazione Ca’ Granda IRCCS, University of Milan, Milan, Italy

²Italian Association for Metals and Biocompatibility Research – A.I.R.M.E.B., Milan, Italy

³Unit of Oral Pathology and Medicine, Ospedale Papa Giovanni XXIII, Bergamo, Bergamo, Italy

⁴Unit of Histology and Pathology, Ospedale Papa Giovanni XXIII, Bergamo, Bergamo, Italy

Gian Paolo Bombeccari¹ – D.D.S.

Gianpaolo Guzzi² – D.D.S.

Umberto Mariani³ – M.D.

Andrea Gianatti⁴ – M.D.

Diego Ruffoni¹ – D.D.S.

Franco Santoro¹ – M.D., D.D.S.

Francesco Spadari¹ – M.D., D.D.S.

Address correspondence to Dr. Gianpaolo Bombeccari, Department of Biomedical, Surgical and Dental Sciences, Ospedale Maggiore Policlinico Fondazione Ca’ Granda IRCCS, University of Milan, Via Della Commenda 10, 20122 Milan, Italy.

E-mail address: gpbombeccari@libero.it



	Baltic Dental and Maxillofacial Journal

September, 2015, Vol. 17, No. 3 CONTENTS REVIEWS Cleft-related nose deformation evaluation and measurement methods. Literature review Ieva Bagante, Ilze Akota 75-83 SCIENTIFIC ARTICLES Neuromuscular evaluation in young patients with unilateral posterior crossbite before and after rapid maxillary expansion Cinzia Maspero, Lucia Giannini, Guido Galbiati, Laima Kairyte, Giampietro Farronato 84-88 CASE REPORTS Medication – related osteonecrosis of the jaws. The first reported cases in the Baltic States and a literature review Linas Zaleckas, Mindaugas Stacevičius, Dovilė Proškutė, Jurgita Povilaitytė 89-96 Synovial chondromatosis in the temporomandibular joint: case report with review of the literature Oksana Ivask, Edvitar Leibur, Ülle Voog-Oras 97-101 Trichoadenoma of the upper lip Gian Paolo Bombeccari, Gianpaolo Guzzi, Umberto Mariani, Andrea Gianatti, Diego Ruffoni, Franco Santoro, Francesco Spadari 102-104 © 2015 Stomatologija		Stomatologija 2015; 17 (3): 102-104 76 KB Trichoadenoma of the upper lip Gian Paolo Bombeccari, Gianpaolo Guzzi, Umberto Mariani, Andrea Gianatti, Diego Ruffoni, Franco Santoro, Francesco Spadari Summary Background. Trichoadenoma of Nikolowski, who describe the first cases in 1958, is a rare and benign tumor of the hair follicle. It is well-differentiated and slowly-growing. The clinical appearance of Trichoadenoma (TA) can be similar to basal cell carcinoma or epidermal cyst. Results. We describe a 44-year-old male who was referred for nodular lesion on the upper lip and a TA was diagnosed. Oral examination showed exophytic yellow mass located between mucous membrane of the upper lip and vestibular gingiva, 1.2 per 0.8 cm. Anamnestic data was non-contributory. An excisional biopsy of the lesion was performed. Microscopically, the lesion consisted of multiple keratinous cysts lined with stratified squamous epithelium and intermingled with solid islands of basaloid cells lying within sclerotic stroma. The pathological diagnosis was TA. The surgical wound healed uneventfully. Conclusion. Because the lesion is unique, it is uncertain how aggressive or indolent the tumor might be. Therefore, the microscopical analysis is mandatory. At the best of our knowledge, this is the second case of trichoadenoma of the lip. Key words: lip lesion, oral nodule, lip tumor, oral tumor, oral follicular hamartoma. Received: 28 07 2013 Accepted for publishing: 28 09 2015 ¹Department of Biomedical, Surgical and Dental Sciences, Ospedale Maggiore Policlinico Fondazione Ca’ Granda IRCCS, University of Milan, Milan, Italy ²Italian Association for Metals and Biocompatibility Research – A.I.R.M.E.B., Milan, Italy ³Unit of Oral Pathology and Medicine, Ospedale Papa Giovanni XXIII, Bergamo, Bergamo, Italy ⁴Unit of Histology and Pathology, Ospedale Papa Giovanni XXIII, Bergamo, Bergamo, Italy Gian Paolo Bombeccari¹ – D.D.S. Gianpaolo Guzzi² – D.D.S. Umberto Mariani³ – M.D. Andrea Gianatti⁴ – M.D. Diego Ruffoni¹ – D.D.S. Franco Santoro¹ – M.D., D.D.S. Francesco Spadari¹ – M.D., D.D.S. Address correspondence to Dr. Gianpaolo Bombeccari, Department of Biomedical, Surgical and Dental Sciences, Ospedale Maggiore Policlinico Fondazione Ca’ Granda IRCCS, University of Milan, Via Della Commenda 10, 20122 Milan, Italy. E-mail address: gpbombeccari@libero.it