SCIENTIFIC ARTICLES

Heritability estimates of dental arch parameters in Lithuanian twins
Vilma Švalkauskienė, Kastytis Šmigelskas, Loreta Šalomskienė, Irena Andriuškevičiūtė, Aurelija Šalomskienė, Arūnas Vasiliauskas, Antanas Šidlauskas
3-8

Antimicrobial activity of silver and gold in toothpastes: A comparative analysis
Jonas Junevičius, Juozas Žilinskas, Kęstutis Česaitis, Gabrielė Česaitienė, Darius Gleiznys, Žaneta Maželienė
9-12

A revised approach of human mastication function rehabilitation through monotypical mastication analysis
Gediminas Skirbutis, Algimantas Surna, Rimantas Barauskas, Rimas Surna, Alvydas Gleiznys
13-20

REVIEWS

Oral manifestations of HIV disease: A review
Daiva Aškinytė, Raimonda Matulionytė, Arūnas Rimkevičius
21-28

CASE REPORTS

Odontogenic maxillary sinusitis obscured by midfacial trauma
Regimantas Simuntis, Ričardas Kubilius, Silvija Ryškienė, Saulius Vaitkus
29-32

Stomatologija 2015; 17 (1): 9-12 264 KB

Antimicrobial activity of silver and gold in toothpastes: A comparative analysis

Jonas Junevičius, Juozas Žilinskas, Kęstutis Česaitis, Gabrielė Česaitienė, Darius Gleiznys, Žaneta Maželienė

Summary

Objective. In this study, we compared the antimicrobial activity of identical toothpastes differing only in silver or gold nanoparticles against the activity of one of the common toothpastes containing a chemical active ingredient. We also compared the active concentrations of the toothpastes.

Methods. For this study, we selected “Royal Denta” toothpastes containing silver and gold particles, and the “Blend-A-Med Complete” toothpaste containing zinc citrate as the active ingredient. We used 8 standard microorganism cultures on the basis of their individual mechanisms of protection. The antimicrobial activity of each studied preparation was evaluated at 9 concentrations.

Results. Most effective against gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis) was the “Silver Technology” – MIC was 0.004–0.0015 g/mL. Neither “Silver Technology” nor “Orange and Gold Technology” had any effect on Escherichia coli or Proteus mirabilis. Antimicrobial activity against the motile bacterium Proteus mirabilis was observed in “Silver Technology”, “Orange and Gold Technology”, and “Blend-A-Med Complete” – the MIC was 0.015 g/mL or lower. No antimicrobial activity against Candida albicans fungus at the studied concentrations was observed in the “Orange and Gold Technology”. The toothpaste “Blend-A-Med” demonstrated the most effective antimicrobial activity – the MIC of 0.0015 g/mL and 0.015 g/mL inhibited Staphylococcus aureus and Enterococcus faecalis, respectively, and the MIC of 0.15 g/mL inhibited the growth of the bacteria Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and fungus Candida albicans.

Conclusions. Silver in toothpaste has a greater antimicrobial effect than gold, but its effect is still inferior to that of a chemical antimicrobial agent.

---

¹Clinical Department of Dental and Maxillofacial Orthopedics, Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences

²Private practice in odontology

³Faculty of Odontology, Medical Academy, Lithuanian University of Health Sciences

⁴Institute of Microbiology and Virology, Faculty of Veterinary Medicine, Veterinary Academy, Lithuanian University of Health Sciences

Jonas Junevičius¹ – D.D.S., PhD, lect.

Juozas Žilinskas¹ – D.D.S., PhD, lect.

Kęstutis Česaitis² – D.D.S.

Gabrielė Česaitienė³ – student

Darius Gleiznys¹ – D.D.S.

Žaneta Maželienė⁴ – M.D., assist. prof.

Address correspondence to: Kęstutis Česaitis, Ukmergės g. 32-18, Kaunas, Lithuania.

E-mail address: kcesaitis@gmail.com