|Baltic Dental and Maxillofacial Journal|
September, 2017, Vol. 19, No. 3
Family history and risk factors for cleft lip and palate patients and their associated anomalies
Serum and salivary lactate dehydrogenase levels as biomarkers of tissue damage among cigarette smokers. A bochemical study
© 2017 Stomatologija
Stomatologija 2017; 19 (3):91-6 141 KB
Serum and salivary lactate dehydrogenase levels as biomarkers of tissue damage among cigarette smokers. A biochemical study
Kumuda Rao1, Subhas G. Babu1, Urvashi A. Shetty2, Renita Lorina Castelino1, Shishir Ram Shetty3
Objective. To estimate the serum and salivary lactate dehydrogenase levels in cigarette smokers and non-smokers.
Materials and Methods. In this study lactate dehydrogenase levels were estimated in 30 healthy individuals with no tobacco related habits and in 30 patients with history of smoking cigarettes for a minimum of 2 years using Spectrophotometry.
Results. The mean values for serum and salivary lactate dehydrogenase levels were higher in cigarette smokers when compared to non-smokers. Serum lactate dehydrogenase levels on comparison between the groups was statistically significant (p=0.04). The values of salivary lactate dehydrogenase levels between the groups was highly significant (p<0.001).
Conclusion. Cigarette smoking leads to an increase in serum as well as salivary Lactate dehydrogenase levels as indicator of tissue damage in the oral cavity. The present study indicates saliva as a better test medium than serum in determination of lactate dehydrogenase levels.
Key words: antioxidants, saliva, serum, cigarette smoking, lactate dehydrogenase.
Received: 19 08 2016
Accepted for publishing: 28 09 2017
1Department of Oral Medicine and Radiology, A. B. Shetty Memorial Institute of Dental Sciences, Nitte University, Deralakatte, India
2Department of Oral Pathology and Microbiology, A. B. Shetty Memorial Institute of Dental Sciences, Nitte University, Deralakatte, India
3Department of Oral Medicine and Radiology, Gulf Medical University, Ajman, United Arab Emirates
Address correspondence to Dr. Kumuda Rao, A. B. Shetty Memorial Institute of Dental Sciences, Nitte University, Deralakatte, Mangalore, Karnataka, India.
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